Smad7^tm1Gkh
Targeted Allele Detail

Summary

• Symbol: Smad7^tm1Gkh
• Name: SMAD family member 7; targeted mutation 1, Goran K Hansson
• MGI ID: MGI:5585420
• Synonyms: Smad7^fl
• Gene: Smad7 Location: Chr18:75500600-75529006 bp, + strand Genetic Position: Chr18, 51.06 cM, cytoband E2
• Alliance: Smad7^tm1Gkh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213468
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 1 and 2 were floxed. (J:213468)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smad7 Mutation: 53 strains or lines available

References

• Original: J:213468 Gistera A, et al., Transforming growth factor-beta signaling in T cells promotes stabilization of atherosclerotic plaques through an interleukin-17-dependent pathway. Sci Transl Med. 2013 Jul 31;5(196):196ra100
• All: 1 reference(s)