P3h2^tm1Hpb
Targeted Allele Detail

Summary

• Symbol: P3h2^tm1Hpb
• Name: prolyl 3-hydroxylase 2; targeted mutation 1, Hans Peter Bachinger
• MGI ID: MGI:5585628
• Gene: P3h2 Location: Chr16:25778038-25924534 bp, - strand Genetic Position: Chr16, 17.63 cM
• Alliance: P3h2^tm1Hpb page

Maternal blood invades the ectoplacental cone of E6.5 P3h2^tm1Hpb/P3h2^tm1Hpb embryos

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:206377
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout) Mutation: Insertion A neomycin resistance cassette was inserted into exon 2. (J:206377)

Generation of the P3h2^tm1Hpb allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any P3h2 Mutation: 35 strains or lines available

References

• Original: J:206377 Pokidysheva E, et al., Biological role of prolyl 3-hydroxylation in type IV collagen. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):161-6
• All: 1 reference(s)