Acap1^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Acap1^{tm1.1(KOMP)Vlcg}
• Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 1; targeted mutation 1.1, Velocigene
• MGI ID: MGI:5585643
• Gene: Acap1 Location: Chr11:69772393-69786365 bp, - strand Genetic Position: Chr11, 42.91 cM
• Alliance: Acap1^{tm1.1(KOMP)Vlcg} page
• IMPC: Acap1 gene page

Mutation origin

• Mutant Cell Line: 18731A-C12
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 13756bp between positions 69695082-69708837 of Chromosome 11 (Genome Build37), and subsequent Cre-mediated excision deleted the neomycin selection cassette. (J:136110, J:188991)

Expression

In Mice Carrying this Mutation:	40 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Acap1 Mutation: 37 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 5 reference(s)