Msi2^tm1.1Cjl
Targeted Allele Detail

Summary

• Symbol: Msi2^tm1.1Cjl
• Name: musashi RNA-binding protein 2; targeted mutation 1.1, Christopher J Lengner
• MGI ID: MGI:5588139
• Synonyms: Msi2^f, Msi2^flox
• Gene: Msi2 Location: Chr11:88230208-88609197 bp, - strand Genetic Position: Chr11, 52.4 cM, cytoband B5-C
• Alliance: Msi2^tm1.1Cjl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208349
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 1 through 4 were floxed. Cre-mediated recombination removed the neomycin resistance cassette inserted into intron 5. (J:208349)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Msi2 Mutation: 781 strains or lines available

References

• Original: J:208349 Park SM, et al., Musashi-2 controls cell fate, lineage bias, and TGF-beta signaling in HSCs. J Exp Med. 2014 Jan 13;211(1):71-87
• All: 9 reference(s)