Ttc36^em1Qz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ttc36^em1Qz
• Name: tetratricopeptide repeat domain 36; endonuclease-mediated mutation 1, Qin Zhou
• MGI ID: MGI:5588394
• Synonyms: Ttc36^TM1
• Gene: Ttc36 Location: Chr9:44710697-44714248 bp, - strand Genetic Position: Chr9, 24.84 cM
• Alliance: Ttc36^em1Qz page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• Mutation details: TALEN targeted mutagenesis results in the loss of two base pairs (G and T) resulting in premature termination of translation prior to the last 15 remaining amino acids. Western blot analysis confirmed the absence of protein expression in the kidney. (J:212206)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ttc36 Mutation: 9 strains or lines available

References

• Original: J:212206 Liu Y, et al., A modified TALEN-based strategy for rapidly and efficiently generating knockout mice for kidney development studies. PLoS One. 2014;9(1):e84893
• All: 2 reference(s)