Tg(CD2-Mir181d)38Oers
Transgene Detail

Summary

• Symbol: Tg(CD2-Mir181d)38Oers
• Name: transgene insertion 38, Nicolai S C van Oers
• MGI ID: MGI:5588400
• Synonyms: Tg-38
• Transgene: Tg(CD2-Mir181d)38Oers Location: unknown
• Alliance: Tg(CD2-Mir181d)38Oers page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CD2-Mir181d)38Oers expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mir181d (MGI:3709847)

• Mutation details: The human promoter (VA-hCD2) drives thymocyte and peripheral T cell-specific expression of a 394 bp fragment with an intact Mir181d but lacking the first 28 nulceotides of Mir181c. Lines 8 and 28 were generated with 2- and 6-fold expression, respectively. (J:212571)

Schematic of the Tg(CD2-Mir181d)38Oers transgene

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:212571 Belkaya S, et al., Transgenic expression of microRNA-181d augments the stress-sensitivity of CD4(+)CD8(+) thymocytes. PLoS One. 2014;9(1):e85274
• All: 1 reference(s)