Uts2^tm1Ags
Targeted Allele Detail

Summary

• Symbol: Uts2^tm1Ags
• Name: urotensin 2; targeted mutation 1, Adel Giaid Schwertani
• MGI ID: MGI:5588699
• Synonyms: UII KO
• Gene: Uts2 Location: Chr4:151081554-151086267 bp, + strand Genetic Position: Chr4, 81.53 cM, cytoband E1
• Alliance: Uts2^tm1Ags page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214289
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A targeting vector containing an IRES sequence, lacZ and a Pgk-NEO cassette was used to disrupt half of exon 4 and all of exons 5 and 6. (J:214289)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Uts2 Mutation: 14 strains or lines available

References

• Original: J:214289 Kiss RS, et al., Urotensin II differentially regulates macrophage and hepatic cholesterol homeostasis. Peptides. 2011 May;32(5):956-63
• All: 2 reference(s)