Tspo^tm1.1Guwu
Targeted Allele Detail

Summary

• Symbol: Tspo^tm1.1Guwu
• Name: translocator protein; targeted mutation 1.1, Richard Banati
• MGI ID: MGI:5603424
• Gene: Tspo Location: Chr15:83447793-83458404 bp, + strand Genetic Position: Chr15, 39.4 cM
• Alliance: Tspo^tm1.1Guwu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:219189
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A loxP site was inserted in intron 1 and a neomycin selection cassette followed by a second loxP site was inserted in intron 3. Exons 2 and 3 as well as the selection cassette were removed by cre excision. (J:219189)

Generation of the Tspo^tm1.1Guwu allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tspo Mutation: 16 strains or lines available

References

• Original: J:219189 Banati RB, et al., Positron emission tomography and functional characterization of a complete PBR/TSPO knockout. Nat Commun. 2014;5:5452
• All: 5 reference(s)