Akap6tm1.2Mskf
Targeted Allele Detail
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Symbol: |
Akap6tm1.2Mskf |
Name: |
A kinase anchor protein 6; targeted mutation 1.2, Michael S Kapiloff |
MGI ID: |
MGI:5603562 |
Gene: |
Akap6 Location: Chr12:52746166-53202382 bp, + strand Genetic Position: Chr12, 22.18 cM
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Alliance: |
Akap6tm1.2Mskf page
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Germline Transmission: |
Earliest citation of germline transmission:
J:214288
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The targeting vector contains a FRT-flanked neomycin cassette followed by a loxP site upstream exon 9 and loxP downstream of exon 9. Flpe mediated recombination removed the FRT-flanked neo cassette leaving exon 9 floxed. Cre mediated recombination removed exon 9.
(J:214288)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Akap6 Mutation: |
113 strains or lines available
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Original: |
J:214288 Kritzer MD, et al., The scaffold protein muscle A-kinase anchoring protein beta orchestrates cardiac myocyte hypertrophic signaling required for the development of heart failure. Circ Heart Fail. 2014 Jul;7(4):663-72 |
All: |
1 reference(s) |
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