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Gt(ROSA)26Sortm1(Tbx1)Rche
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(Tbx1)Rche
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ellen R Richie
MGI ID: MGI:5604017
Synonyms: R26iTbx, R26iTbx1
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(Tbx1)Rche page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:214094
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, Reporter)
Mutation:    Insertion
 
Mutation detailsThe targeting construct inserted into the locus a full-length mouse Tbx1 cDNA and an IRES-EGFP downstream of a floxed beta-geo stop cassette. Cre excision of the stop cassette results in expression of Tbx1 and EGFP. (J:214094)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  993 strains or lines available
References
Original:  J:214094 Reeh KA, et al., Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis. Development. 2014 Aug;141(15):2950-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory