Nrxn1^tm5Sud
Targeted Allele Detail

Summary

• Symbol: Nrxn1^tm5Sud
• Name: neurexin I; targeted mutation 5, Thomas C Sudhof
• MGI ID: MGI:5605040
• Synonyms: Nrxn1^flox
• Gene: Nrxn1 Location: Chr17:90341059-91400499 bp, - strand Genetic Position: Chr17, 59.73 cM
• Alliance: Nrxn1^tm5Sud page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a loxP site upstream of exon 21, and a frt-flanked neomycin resistance (neo) cassette, followed by a second loxP site, downstream of exon 21. Also, splice site 4, upstream of exon 21, was mutated to a canonical splice acceptor sequence. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nrxn1 Mutation: 98 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)