S100a5^tm1.1Mom
Targeted Allele Detail

Summary

• Symbol: S100a5^tm1.1Mom
• Name: S100 calcium binding protein A5; targeted mutation 1.1, Peter Mombaerts
• MGI ID: MGI:5605391
• Synonyms: S100a5-delta-tauGFP, S100a5-tauGFP
• Gene: S100a5 Location: Chr3:90515830-90519087 bp, + strand Genetic Position: Chr3, 39.27 cM, cytoband F1-F2
• Alliance: S100a5^tm1.1Mom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215302
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The two coding exons and intervening intron were deleted and replaced with a tau-GFP reporter and a loxP flanked pgk-neo cassette, and a subsequent cross to a Tg(EIIa-cre)Lmgd bearing strain excised the neomycin selection casssette yielding a GFP reporter that gives activity-dependent fluorescent marking of olfactory sensory neurons (J:215302)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any S100a5 Mutation: 8 strains or lines available

References

• Original: J:215302 McClintock TS, et al., In vivo identification of eugenol-responsive and muscone-responsive mouse odorant receptors. J Neurosci. 2014 Nov 19;34(47):15669-78
• All: 1 reference(s)