Susd6^tm1.1Geno
Targeted Allele Detail

Summary

• Symbol: Susd6^tm1.1Geno
• Name: sushi domain containing 6; targeted mutation 1.1, Genoway
• MGI ID: MGI:5606033
• Synonyms: DRAGO^-
• Gene: Susd6 Location: Chr12:80837306-80927607 bp, + strand Genetic Position: Chr12, 37.05 cM
• Alliance: Susd6^tm1.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:210814
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP-flanked neomycin selection cassette was 3' to exon 3 and a sigle loxP site was inserted 5' to exon 5. Cre-mediated recombination in ES cells resulted in the deletion of the selection cassette and exons 3-5. (J:210814)

Tumor Data

List all tumor models in MMHCdb carrying Susd6^tm1.1Geno

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Susd6 Mutation: 133 strains or lines available

References

• Original: J:210814 Polato F, et al., DRAGO (KIAA0247), a new DNA damage-responsive, p53-inducible gene that cooperates with p53 as oncosupprossor. J Natl Cancer Inst. 2014 Apr;106(4):dju053
• All: 1 reference(s)