Srf^tm1.1Wtp
Targeted Allele Detail

Summary

• Symbol: Srf^tm1.1Wtp
• Name: serum response factor; targeted mutation 1.1, William T Pu
• MGI ID: MGI:5606035
• Synonyms: CVDC/B2B program mutation, Srf-flbio
• Gene: Srf Location: Chr17:46859255-46867101 bp, - strand Genetic Position: Chr17, 22.9 cM
• Alliance: Srf^tm1.1Wtp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185868
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae
• Project Collection: B2B/CvDC

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a FLAG/bio epitope tag and a frt-flanked neomycin resistance (neo) cassette at the endogenous Srf stop codon and upstream of the 3' UTR. FLP mediated recombination removed the FRT-flanked neo cassette. (J:185868)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Srf Mutation: 27 strains or lines available

References

• Original: J:185868 Schramm C, Information about alleles developed by members of the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program. MGI Direct Data Submission. 2012
• All: 3 reference(s)