Mef2c^tm1.1Wtp
Targeted Allele Detail

Summary

• Symbol: Mef2c^tm1.1Wtp
• Name: myocyte enhancer factor 2C; targeted mutation 1.1, William T Pu
• MGI ID: MGI:5606040
• Synonyms: CVDC/B2B program mutation, Mef2c-flbio
• Gene: Mef2c Location: Chr13:83652153-83815199 bp, + strand Genetic Position: Chr13, 43.68 cM
• Alliance: Mef2c^tm1.1Wtp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185868
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae
• Project Collection: B2B/CvDC

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a FLAG/bio epitope tag and a frt-flanked neomycin resistance (neo) cassette at the endogenous Mef2c stop codon and upstream of the 3' UTR. FLP mediated recombination removed the FRT-flanked neo cassette. (J:185868)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mef2c Mutation: 34 strains or lines available

References

• Original: J:185868 Schramm C, Information about alleles developed by members of the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program. MGI Direct Data Submission. 2012
• All: 3 reference(s)