Adamts20^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Adamts20^m3Btlr
• Name: ADAM metallopeptidase with thrombospondin type 1 motif 20; mutation 3, Bruce Beutler
• MGI ID: MGI:5607745
• Synonyms: pikachu
• Gene: Adamts20 Location: Chr15:94166177-94329966 bp, - strand Genetic Position: Chr15, 48.2 cM
• Alliance: Adamts20^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: The molecular lesion is a T to A transversion at base pair 94,345,990 (v38) on chromosome 15 or base pair 119,429 in the GenBank genomic region NC_000081. This corresponds to nucleotide (nt) 2,116 in the mRNA sequence NM_177431 (isoform 1), within exon 13 of 39 total exons, and to nt 2,116 in the mRNA sequence NM_00164785 (isoform 2), within exon 13 of 28 total exons. The mutation results in a cysteine (C) to serine (S) substitution at amino acid position 619 (C619S) in both Adamts20 protein variants. (J:216051)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adamts20 Mutation: 93 strains or lines available

References

• Original: J:216051 Reyna C, et al., Mutagenetix entry for pikachu. Updated on December 16, 2014. MGI Direct Data Submission. 2014
• All: 1 reference(s)