Tg(CAG-RFP,Acr-EGFP)RBGS002Osb
Transgene Detail
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| Symbol: |
Tg(CAG-RFP,Acr-EGFP)RBGS002Osb |
| Name: |
transgene insertion RBGS002, Research Institute for Microbial Diseases, Osaka University |
| MGI ID: |
MGI:5607931 |
| Synonyms: |
Tg(CAG/Su9-DsRed2,Acr3-EGFP)RBGS002Osb |
| Transgene: |
Tg(CAG-RFP,Acr-EGFP)RBGS002Osb Location: unknown
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| Alliance: |
Tg(CAG-RFP,Acr-EGFP)RBGS002Osb page
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| Strain of Origin: |
C57BL/6 x DBA/2
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: Two transgenic constructs were coinjected. The first construct has the CAG promoter fused to a mitochondrial import sequence (Atp5g1) driving expression of RFP (DsRed2). The second construct has the acrosin promoter with a proacrosin signal sequence driving expression of GFP. The sperm head is green prior to the acrosome reaction, after acrosome reaction GFP expression is lost. RFP expression is seen in the mitochondria in the midpiece of the sperm.
(J:216056)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:216056 Hasuwa H, et al., Transgenic mouse sperm that have green acrosome and red mitochondria allow visualization of sperm and their acrosome reaction in vivo. Exp Anim. 2010;59(1):105-7 |
| All: |
38 reference(s) |
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Analysis Tools
