Hras^tm1Rak
Targeted Allele Detail

Summary

• Symbol: Hras^tm1Rak
• Name: Harvey rat sarcoma virus oncogene; targeted mutation 1, Raju Kucherlapati
• MGI ID: MGI:5608504
• Synonyms: GV, Haras^G12V
• Gene: Hras Location: Chr7:140770839-140773938 bp, - strand Genetic Position: Chr7, 86.48 cM
• Alliance: Hras^tm1Rak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: The targeting vector contains a loxP-flanked neomycin cassette upstream of a modified exon 2, which contains a G12V mutation with a unique restriction site. The mutation results in a glycine to valine change at position 12. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hras Mutation: 30 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)