Rara^tm1.1Ybe
Targeted Allele Detail

Summary

• Symbol: Rara^tm1.1Ybe
• Name: retinoic acid receptor, alpha; targeted mutation 1.1, Yasmine Belkaid
• MGI ID: MGI:5608510
• Synonyms: Raralpha^fl
• Gene: Rara Location: Chr11:98818644-98865768 bp, + strand Genetic Position: Chr11, 62.76 cM, cytoband D-E1
• Alliance: Rara^tm1.1Ybe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:207485
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 3 was flanked with loxP sites and FRT (neo) and F3 (puro) flanked selection cassettes were inserted into intons 2 and 3, respectively. Flp mediated recombination removed the selection cassettes. (J:207485)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rara Mutation: 79 strains or lines available

References

• Original: J:207485 Spencer SP, et al., Adaptation of innate lymphoid cells to a micronutrient deficiency promotes type 2 barrier immunity. Science. 2014 Jan 24;343(6169):432-7
• All: 2 reference(s)