Rab11a^tm1.1Ngao
Targeted Allele Detail

Summary

• Symbol: Rab11a^tm1.1Ngao
• Name: RAB11A, member RAS oncogene family; targeted mutation 1.1, Nan Gao
• MGI ID: MGI:5608786
• Synonyms: Rab11a^fl
• Gene: Rab11a Location: Chr9:64622582-64645038 bp, - strand Genetic Position: Chr9, 34.87 cM, cytoband C
• Alliance: Rab11a^tm1.1Ngao page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215917
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted at 242 bp downstream of the second exon and a and a FRT-flanked PGK-neo cassette followed by a second loxP site was introduced at 210 bp downstream of the fourth exon. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:215917, J:222158)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rab11a Mutation: 14 strains or lines available

References

• Original: J:215917 Yu S, et al., TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis. EMBO J. 2014 Sep 1;33(17):1882-95
• All: 10 reference(s)