Slc34a3^tm1.1Nhch
Targeted Allele Detail

Summary

• Symbol: Slc34a3^tm1.1Nhch
• Name: solute carrier family 34 (sodium phosphate), member 3; targeted mutation 1.1, Nati Hernando
• MGI ID: MGI:5609132
• Synonyms: Slc34a3^f
• Gene: Slc34a3 Location: Chr2:25118909-25124282 bp, - strand Genetic Position: Chr2, 17.09 cM
• Alliance: Slc34a3^tm1.1Nhch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208414
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT flanked pgk-neo cassette and loxP site were inserted upstream of exon 4 and a loxP site was inserted downstream of exon 12 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:208414)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc34a3 Mutation: 24 strains or lines available

References

• Original: J:208414 Myakala K, et al., Renal-specific and inducible depletion of NaPi-IIc/Slc34a3, the cotransporter mutated in HHRH, does not affect phosphate or calcium homeostasis in mice. Am J Physiol Renal Physiol. 2014 Apr;306(8):F833-43
• All: 1 reference(s)