Kif13b^tm1.1Noh
Targeted Allele Detail

Summary

• Symbol: Kif13b^tm1.1Noh
• Name: kinesin family member 13B; targeted mutation 1.1, Nobutaka Hirokawa
• MGI ID: MGI:5609275
• Gene: Kif13b Location: Chr14:64889633-65047067 bp, + strand Genetic Position: Chr14, 33.77 cM, cytoband C3
• Alliance: Kif13b^tm1.1Noh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208261
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 4 and a floxed splice acceptor site, IRES, and Betageo cassette was inserted downstream of exon 5 via homologous recombination. Cre mediated recombination removed exons 4 and 5 and the selection cassette. (J:208261)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif13b Mutation: 109 strains or lines available

References

• Original: J:208261 Kanai Y, et al., KIF13B enhances the endocytosis of LRP1 by recruiting LRP1 to caveolae. J Cell Biol. 2014 Feb 3;204(3):395-408
• All: 1 reference(s)