Dnaaf6rt^tm1.2Hmd
Targeted Allele Detail

Summary

• Symbol: Dnaaf6rt^tm1.2Hmd
• Name: dynein axonemal assembly factor 6, retrotransposed; targeted mutation 1.2, Hiroshi Hamada
• MGI ID: MGI:5609303
• Synonyms: Dnaaf6^tm1.2Hh, Pih1d3^tm1.1Hmd
• Gene: Dnaaf6rt Location: Chr1:31261920-31263368 bp, + strand Genetic Position: Chr1, 11.56 cM, cytoband A5
• Alliance: Dnaaf6rt^tm1.2Hmd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208266
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A Myc epitope tag, an IRES lacZ expression cassette and an FRT flanked PGK-neo were inserted downstream of the single exon. LoxP sites were inserted to flank the entire modified gene. The entire gene as well as the inserted expression cassette were subsequently excised using cre recombinase. (J:208266)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dnaaf6rt Mutation: 19 strains or lines available

References

• Original: J:208266 Dong F, et al., Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm. J Cell Biol. 2014 Jan 20;204(2):203-13
• All: 1 reference(s)