Pou5f1^tm1Jnic
Targeted Allele Detail

Summary

• Symbol: Pou5f1^tm1Jnic
• Name: POU domain, class 5, transcription factor 1; targeted mutation 1, Jennifer Nichols
• MGI ID: MGI:5610123
• Synonyms: Oct4^LoxP
• Gene: Pou5f1 Location: Chr17:35816929-35821674 bp, + strand Genetic Position: Chr17, 18.69 cM
• Alliance: Pou5f1^tm1Jnic page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208425
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted in intron 1 and a floxed neo cassette was inserted downstream of exon 5 via homologous recombination. (J:208425)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pou5f1 Mutation: 82 strains or lines available

References

• Original: J:208425 Le Bin GC, et al., Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst. Development. 2014 Mar;141(5):1001-10
• All: 5 reference(s)