Dmrta2^tm1Ejbd
Targeted Allele Detail

Summary

• Symbol: Dmrta2^tm1Ejbd
• Name: doublesex and mab-3 related transcription factor like family A2; targeted mutation 1, Eric J Bellefroid
• MGI ID: MGI:5613136
• Synonyms: Dmrt5-
• Gene: Dmrta2 Location: Chr4:109835250-109840884 bp, + strand Genetic Position: Chr4, 51.37 cM
• Alliance: Dmrta2^tm1Ejbd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215514
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance selection cassette replaced part of exon 1 through the coding sequence of exon 3. RT-PCR confirmed the absence of transcript expression in E15 brain and adult testis. (J:215514)

Expression

In Mice Carrying this Mutation:	124 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	14 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dmrta2 Mutation: 15 strains or lines available

References

• Original: J:215514 Saulnier A, et al., The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex. 2013 Nov;23(11):2552-67
• All: 2 reference(s)