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Adam23tm1.1Mejr
Targeted Allele Detail
Summary
Symbol: Adam23tm1.1Mejr
Name: a disintegrin and metallopeptidase domain 23; targeted mutation 1.1, Dies Meijer
MGI ID: MGI:5613204
Synonyms: Adam23Lox
Gene: Adam23  Location: Chr1:63484880-63635263 bp, + strand  Genetic Position: Chr1, 32.31 cM
Alliance: Adam23tm1.1Mejr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:208847
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 1 and an FRT flanked selection cassette and loxP site were inserted downstream of exon 1. Flp mediated recombination removed the selection cassette. (J:208847)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adam23 Mutation:  63 strains or lines available
References
Original:  J:208847 Kegel L, et al., Functional phylogenetic analysis of LGI proteins identifies an interaction motif crucial for myelination. Development. 2014 Apr;141(8):1749-56
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory