Adam23^tm1.1Mejr
Targeted Allele Detail

Summary

• Symbol: Adam23^tm1.1Mejr
• Name: a disintegrin and metallopeptidase domain 23; targeted mutation 1.1, Dies Meijer
• MGI ID: MGI:5613204
• Synonyms: Adam23^Lox
• Gene: Adam23 Location: Chr1:63484880-63635263 bp, + strand Genetic Position: Chr1, 32.31 cM
• Alliance: Adam23^tm1.1Mejr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208847
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and an FRT flanked selection cassette and loxP site were inserted downstream of exon 1. Flp mediated recombination removed the selection cassette. (J:208847)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adam23 Mutation: 62 strains or lines available

References

• Original: J:208847 Kegel L, et al., Functional phylogenetic analysis of LGI proteins identifies an interaction motif crucial for myelination. Development. 2014 Apr;141(8):1749-56
• All: 3 reference(s)