Gt(ROSA)26Sor^{tm4(Wnt7b)Flng}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm4(Wnt7b)Flng}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Fanxin Long
• MGI ID: MGI:5613577
• Synonyms: R26-Wnt7b
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm4(Wnt7b)Flng} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm4(Wnt7b)Flng} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Wnt7b

• Mutation details: A construct consisting of a floxed pgk-neo-3xpolyA sequence followed by Wnt7b cDNA, IRES, and EGFP was inserted into intron 1. (J:208766)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:208766 Chen J, et al., WNT7B promotes bone formation in part through mTORC1. PLoS Genet. 2014 Jan;10(1):e1004145
• All: 4 reference(s)