Ptprc^m1Smv
Chemically induced Allele Detail

Summary

• Symbol: Ptprc^m1Smv
• Name: protein tyrosine phosphatase receptor type C; mutation 1, Silvia M Vidal
• MGI ID: MGI:5613813
• Synonyms: Ptprc^L3x
• Gene: Ptprc Location: Chr1:137990599-138103446 bp, - strand Genetic Position: Chr1, 60.73 cM
• Alliance: Ptprc^m1Smv page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A to T mutation that results in the amino acid substitution of a termination codon for leucine at position 3 (L3X). (J:214487)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptprc Mutation: 189 strains or lines available

References

• Original: J:214487 Caignard G, et al., Genome-wide mouse mutagenesis reveals CD45-mediated T cell function as critical in protective immunity to HSV-1. PLoS Pathog. 2013 Sep;9(9):e1003637
• All: 1 reference(s)