Skor2^tm1Yono
Targeted Allele Detail

Summary

• Symbol: Skor2^tm1Yono
• Name: SKI family transcriptional corepressor 2; targeted mutation 1, Yuichi Ono
• MGI ID: MGI:5613907
• Gene: Skor2 Location: Chr18:76944100-76988037 bp, + strand Genetic Position: Chr18, 51.93 cM
• Alliance: Skor2^tm1Yono page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208769
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Most of exon 1 was replaced with a GFP-neo cassette via homologous recombination. Immunohistochemical analysis confirmed the absence of expression in homozygous mice. (J:208769)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Skor2 Mutation: 45 strains or lines available

References

• Original: J:208769 Nakatani T, et al., The c-Ski family member and transcriptional regulator Corl2/Skor2 promotes early differentiation of cerebellar Purkinje cells. Dev Biol. 2014 Apr 1;388(1):68-80
• All: 2 reference(s)