Ngly1^em4Lutzy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ngly1^em4Lutzy
• Name: N-glycanase 1; endonuclease-mediated mutation 4, Cathy Lutz
• MGI ID: MGI:5614022
• Synonyms: Del040
• Gene: Ngly1 Location: Chr14:6157837-6220449 bp, - strand Genetic Position: Chr14, 7.08 cM, cytoband A2
• Alliance: Ngly1^em4Lutzy page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• Mutation details: The CRISPR/cas9 endonuclease mediated genome editing introduced deletions downstream of amino acid 385 in exon 8. Mice from founder 40 were found to have an 11 bp deletion (CTGGCGATACT) resulting in a frame shift mutation.
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ngly1 Mutation: 39 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 4 reference(s)