Tg(Myh6-TNNI3K)#Tfo
Transgene Detail

Summary

• Symbol: Tg(Myh6-TNNI3K)#Tfo
• Name: transgene insertion, Thomas Force
• MGI ID: MGI:5614260
• Synonyms: Tg-TNNI3K
• Transgene: Tg(Myh6-TNNI3K)#Tfo Location: unknown
• Alliance: Tg(Myh6-TNNI3K)#Tfo page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-TNNI3K)#Tfo expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TNNI3K (51086)

  Tnni3k

  (MGI:2443276)

• Mutation details: The mouse promoter drives cardiac-specific expression of the wild-type human gene. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:213546)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:213546 Vagnozzi RJ, et al., Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart. Sci Transl Med. 2013 Oct 16;5(207):207ra141
• All: 1 reference(s)