Syde1^{tm1c(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Syde1^{tm1c(EUCOMM)Hmgu}
• Name: synapse defective 1, Rho GTPase, homolog 1 (C. elegans); targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:5614299
• Synonyms: mSYD1A^fl
• Gene: Syde1 Location: Chr10:78420337-78427798 bp, - strand Genetic Position: Chr10, 39.72 cM, cytoband C1
• Alliance: Syde1^{tm1c(EUCOMM)Hmgu} page
• IMPC: Syde1 gene page

Mutation origin

• Mutant Cell Line: HEPD0665_7_C10
• Germline Transmission: Earliest citation of germline transmission: J:157065
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: The gene has, from 5' to 3', a frt site, an En2 splice acceptor cassette containing a beta galactosidase sequence, and loxP-flanked neomycin cassette, containing a frt site, inserted downstream of exon 1. A third loxP-site is inserted downstream of exon 4. FLP mediated recombination removed the FRT-flanked beta galactosidase and neo cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:157065)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Syde1 Mutation: 28 strains or lines available

References

• Original: J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015
• All: 2 reference(s)