Chn1^tm1Ito
Targeted Allele Detail

Summary

• Symbol: Chn1^tm1Ito
• Name: chimerin 1; targeted mutation 1, Shigeyoshi Itohara
• MGI ID: MGI:5614423
• Synonyms: alpha-chimaerin^Flox, alpha-Chn^Flox
• Gene: Chn1 Location: Chr2:73441004-73605690 bp, - strand Genetic Position: Chr2, 43.78 cM
• Alliance: Chn1^tm1Ito page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:209606
• Parent Cell Line: MS12 (ES Cell)
• Strain of Origin: C57BL/6NSlc

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 9 and 10 were flanked by loxP sites. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette. (J:209606)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Chn1 Mutation: 44 strains or lines available

References

• Original: J:209606 Borgius L, et al., Spinal glutamatergic neurons defined by EphA4 signaling are essential components of normal locomotor circuits. J Neurosci. 2014 Mar 12;34(11):3841-53
• All: 3 reference(s)