Tnfsf11^gum
Spontaneous Allele Detail

Summary

• Symbol: Tnfsf11^gum
• Name: tumor necrosis factor (ligand) superfamily, member 11; gummy
• MGI ID: MGI:5614816
• Gene: Tnfsf11 Location: Chr14:78514886-78545483 bp, - strand Genetic Position: Chr14, 41.26 cM
• Alliance: Tnfsf11^gum page

Mutation origin

• Strain of Origin: STOCK Tg(Myh6-cre)1Jmk/J

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Inversion
• Mutation details: A spontaneous 4.7 kb inversion from Chromosome 14 78,279,775 bp to 78,284,475 bp (GRCm38/mm10) has breakpoints in the introns between exons 2 and 3 and 4 and 5, leaving the exons intact but exons 3 and 4 inverted. (J:223062)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tnfsf11 Mutation: 32 strains or lines available

References

• Original: J:223062 Palmer K, et al., Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology. Dev Biol. 2016 Jul 15;415(2):216-27
• All: 1 reference(s)