Myocd^tm1(cre)Dzw
Targeted Allele Detail

Summary

• Symbol: Myocd^tm1(cre)Dzw
• Name: myocardin; targeted mutation 1, Da-Zhi Wang
• MGI ID: MGI:5615209
• Synonyms: Myocd^KI
• Gene: Myocd Location: Chr11:65067387-65160815 bp, - strand Genetic Position: Chr11, 40.42 cM
• Alliance: Myocd^tm1(cre)Dzw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217513
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129 x C57BL/6

Mutation description

• Allele Type: Targeted (Recombinase, Reporter)
• Mutations: Insertion, Intragenic deletion
• Myocd^tm1(cre)Dzw expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Myocd (MGI:2137495)

• Mutation details: Exon 1 was replaced with a cre recombinase gene, IRES, EGFP and FRT neomycin resistance cassette. QPCR confirmed the absence of transcript expression in E9.5 hearts. (J:217513)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Myocd (mouse) Summary of all recombinase alleles driven by Myocd. Comparative matrix view of recombinase activities Alliance mouse Myocd gene page

Expression

In Mice Carrying this Mutation:

23 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myocd Mutation: 55 strains or lines available

References

• Original: J:217513 Espinoza-Lewis RA, et al., Generation of a Cre knock-in into the Myocardin locus to mark early cardiac and smooth muscle cell lineages. Genesis. 2014 Oct;52(10):879-87
• All: 1 reference(s)