Rad21l^tm1Yow
Targeted Allele Detail

Summary

• Symbol: Rad21l^tm1Yow
• Name: RAD21-like (S. pombe); targeted mutation 1, Yoshinori Watanabe
• MGI ID: MGI:5615691
• Gene: Rad21l Location: Chr2:151487324-151510453 bp, - strand Genetic Position: Chr2, 74.83 cM
• Alliance: Rad21l^tm1Yow page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:209347
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting vector was designed to disrupt exon 7-9 with a loxP flanked neo cassette. The disruption of exons 7-9 results in a frame shift after amino acid 262. (J:209347)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rad21l Mutation: 34 strains or lines available

References

• Original: J:209347 Ishiguro K, et al., Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes. Genes Dev. 2014 Mar 15;28(6):594-607
• All: 2 reference(s)