Dclre1c^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Dclre1c^m1Btlr
• Name: DNA cross-link repair 1C; mutation 1, Bruce Beutler
• MGI ID: MGI:5615709
• Synonyms: kiwis
• Gene: Dclre1c Location: Chr2:3425168-3465167 bp, + strand Genetic Position: Chr2, 1.93 cM
• Alliance: Dclre1c^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis resulted in an A to G transition at base pair 3,436,475 (v38) on chromosome 2, or base pair 12,684 in the GenBank genomic region NC_000068. The mutation corresponds to residue 431 in the mRNA sequences NM_146114, NM_175683, NM_001110214 within exon 5 of 14, 16, and 15 total exons, respectively. The mutation results in a histidine (H) to arginine (R) substitution at position 115 (H115R). (J:217790)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dclre1c Mutation: 31 strains or lines available

References

• Original: J:217790 Wang KW, et al., Mutagenetix entry for kiwis. MGI Direct Data Submission. 2015
• All: 1 reference(s)