Rorc^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Rorc^m2Btlr
• Name: RAR-related orphan receptor gamma; mutation 1, Bruce Beutler
• MGI ID: MGI:5615712
• Synonyms: macadamias
• Gene: Rorc Location: Chr3:94280106-94305583 bp, + strand Genetic Position: Chr3, 40.56 cM, cytoband F2
• Alliance: Rorc^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A transversion at base pair 94,397,302 (v38) on chromosome 3, or base pair 24,587 in the GenBank genomic region NC_000069. The mutation corresponds to residue 1,598 in the mRNA sequence NM_011281 within exon 11 of 11 total exons. The mutation results in substitution of tyrosine 500 for a premature stop codon (Y500*). (J:217792)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rorc Mutation: 44 strains or lines available

References

• Original: J:217792 Wang KW, et al., Mutagenetix entry for macadamias. MGI Direct Data Submission. 2015
• All: 1 reference(s)