Prkcb^M3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Prkcb^M3Btlr
• Name: protein kinase C, beta; mutation 3, Bruce Beutler
• MGI ID: MGI:5615714
• Synonyms: Almonde
• Gene: Prkcb Location: Chr7:121888327-122233625 bp, + strand Genetic Position: Chr7, 65.75 cM
• Alliance: Prkcb^M3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A transversion at base pair 122,582,449 (v38) on chromosome 7, or base pair 293,370 in the GenBank genomic region NC_000073. The mutation corresponds to residue 1,479 in the mRNA sequence NM_008855 within exon 11 of 17 total exons. The mutation results in a methionine (M) to lysine (K) substitution at position 420 (M420K). (J:217793)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkcb Mutation: 39 strains or lines available

References

• Original: J:217793 Wang KW, et al., Mutagenetix entry for Almonde. MGI Direct Data Submission. 2015
• All: 1 reference(s)