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Sellm1Btlr
Chemically induced Allele Detail
Summary
Symbol: Sellm1Btlr
Name: selectin, lymphocyte; mutation 1, Bruce Beutler
MGI ID: MGI:5615716
Synonyms: dim_sum
Gene: Sell  Location: Chr1:163889556-163908354 bp, + strand  Genetic Position: Chr1, 71.37 cM
Alliance: Sellm1Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis induced a T to A transversion at base pair 164,066,201 (v38) on chromosome 1, or base pair 4,389 in the GenBank genomic region NC_000067. The mutation affects a thymine base 9 nucleotides from exon 4 (out of 9 total exons). The affect of the mutation on expression and localization has not been examined. The mutation is predicted to affect the splice acceptor site of intron 3, resulting in skipping of the 108-base pair exon 4 (encoding amino acids 158-193). Splicing of exon 3 to exon 5 does not generate a frame-shift. (J:217794)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sell Mutation:  42 strains or lines available
References
Original:  J:217794 Zeng M, et al., Mutagenetix entry for dim_sum. MGI Direct Data Submission. 2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory