Traf3^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Traf3^m2Btlr
• Name: TNF receptor-associated factor 3; mutation 2, Bruce Beutler
• MGI ID: MGI:5615721
• Synonyms: bananasplit
• Gene: Traf3 Location: Chr12:111132804-111233587 bp, + strand Genetic Position: Chr12, 60.94 cM, cytoband F
• Alliance: Traf3^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to G transversion at base pair 111,262,036 (v38) on chromosome 12, or base pair 95,667 in the GenBank genomic region NC_000078. The mutation corresponds to residue 2,041 in the mRNA sequence NM_011632 within exon 12 of 12 total exons. The mutation results in an aspartic acid (D) to glutamic acid (E) substitution at position 560 (D560E). (J:217797)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Traf3 Mutation: 42 strains or lines available

References

• Original: J:217797 Wang KW, et al., Mutagenetix entry for bananasplit. MGI Direct Data Submission. 2015
• All: 1 reference(s)