Rr34^tm1.1Lap
Targeted Allele Detail

Summary

• Symbol: Rr34^tm1.1Lap
• Name: regulatory region 34; targeted mutation 1.1, Len Pennacchio
• MGI ID: MGI:5616932
• Synonyms: mm77^tm1.1Lap
• Gene: Rr34 Location: Chr5:122230281-122232831 bp, + strand Genetic Position: Chr5, Syntenic
• Alliance: Rr34^tm1.1Lap page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:252154
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Modified regulatory region, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The 2517 bp long noncoding transcriptional enhancer sequence was replaced with a loxP site flanked neomycin selection cassette which was subsequently removed by cre excision. (J:252154)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rr34 Mutation: 1 strain or line available

References

• Original: J:252154 Dickel DE, et al., Genome-wide compendium and functional assessment of in vivo heart enhancers. Nat Commun. 2016 Oct 5;7:12923
• All: 1 reference(s)