Pomgnt2^tm1Kkat
Targeted Allele Detail

Summary

• Symbol: Pomgnt2^tm1Kkat
• Name: protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2; targeted mutation 1, Koichi Kato
• MGI ID: MGI:5617746
• Synonyms: AGO61-KO
• Gene: Pomgnt2 Location: Chr9:121810675-121825116 bp, - strand Genetic Position: Chr9, 72.78 cM
• Alliance: Pomgnt2^tm1Kkat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215959
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• The first coding exon was replaced with a neomycin resistance cassette. (J:215959)

Expression

In Mice Carrying this Mutation:	14 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pomgnt2 Mutation: 25 strains or lines available

Notes

ES cell line = TT2 or HK3i. This allele was made in either TT2 ES cells, derived from a (C57BL/6NCrlj x CBA/JNCrlj)F1 embryo, or in HK3i ES cells, derived from C57BL/6NJcl. Alternatively, both cell lines may have been used. (J:215959; LARGE, RIKEN Center for Life Science Technologies)

References

• Original: J:215959 Yagi H, et al., AGO61-dependent GlcNAc modification primes the formation of functional glycans on alpha-dystroglycan. Sci Rep. 2013;3:3288
• All: 2 reference(s)