Gt(ROSA)26Sor^{tm1.2(CAG-tdTomato,-EGFP)Pjen}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1.2(CAG-tdTomato,-EGFP)Pjen}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.2, Patricia Jensen
• MGI ID: MGI:5617963
• Synonyms: Gt(ROSA)26Sor^{tm1.2(CAG-tdTomato,-EGFO)Pjen}, RC::RLTG
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1.2(CAG-tdTomato,-EGFP)Pjen} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:226320
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct contains a rox-flanked STOP, frt-flanked STOP and loxP-flanked tdTomato::STOP upstream of the eGFP fluorescent protein, inserted into the Gt(ROSA)26Sor locus. Flp-mediated recombination removed the FRT-flanked STOP. (J:226320)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:226320 Plummer NW, et al., Expanding the power of recombinase-based labeling to uncover cellular diversity. Development. 2015 Dec 15;142(24):4385-93
• All: 8 reference(s)