Tg(Ren-cre)#Kwg
Transgene Detail

Summary

• Symbol: Tg(Ren-cre)#Kwg
• Name: transgene insertion, Kenneth W Gross
• MGI ID: MGI:5617967
• Synonyms: RenCre
• Transgene: Tg(Ren-cre)#Kwg Location: unknown
• Alliance: Tg(Ren-cre)#Kwg page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Ren-cre)#Kwg expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ren1 (MGI:97898)

• Mutation details: The RP23-88k07 BAC was used to generate a transgene in which the mouse promoter drives expression of cre in the pancreas. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:216559)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ren1 (mouse) Summary of all recombinase alleles driven by Ren1. Comparative matrix view of recombinase activities Alliance mouse Ren1 gene page

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:216559 Glenn ST, et al., Conditional deletion of p53 and Rb in the renin-expressing compartment of the pancreas leads to a highly penetrant metastatic pancreatic neuroendocrine carcinoma. Oncogene. 2014 Dec 11;33(50):5706-15
• All: 2 reference(s)