Creb1^tm1.1Khk
Targeted Allele Detail

Summary

• Symbol: Creb1^tm1.1Khk
• Name: cAMP responsive element binding protein 1; targeted mutation 1.1, Klaus Kaestner
• MGI ID: MGI:5618173
• Gene: Creb1 Location: Chr1:64571963-64643707 bp, + strand Genetic Position: Chr1, 32.74 cM, cytoband C1/C5
• Alliance: Creb1^tm1.1Khk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:210887
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted upstream and downstream of exon 11 with neomycin cassette inserted in intron 11. Cre mediated recombination removed neomycin cassette. (J:210887)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Creb1 Mutation: 61 strains or lines available

References

• Original: J:210887 Lee D, et al., The transcription factor CREB has no non-redundant functions in hepatic glucose metabolism in mice. Diabetologia. 2014 Jun;57(6):1242-8
• All: 2 reference(s)