H2-Ab1^g7-em1Ygch
Endonuclease-mediated Allele Detail

Summary

• Symbol: H2-Ab1^g7-em1Ygch
• Name: histocompatibility 2, class II antigen A, beta 1; endonuclease-mediated mutation 1, Yi-Guang Chen
• MGI ID: MGI:5618308
• Synonyms: H2-Ab1^em1Ygch, H2-Ab- line 11
• Gene: H2-Ab1 Location: Chr17:34482201-34488392 bp, + strand Genetic Position: Chr17, 17.98 cM
• Alliance: H2-Ab1^g7-em1Ygch page

Mutation origin

• Strain of Origin: NOD/ShiLtJ

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Zinc-finger nuclease technology generated a 17 bp deletion in exon 2 that disrupts normal expression of this diabetes susceptibility allele. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any H2-Ab1 Mutation: 83 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)