About   Help   FAQ
Alms1m1Btlr
Chemically induced Allele Detail
Summary
Symbol: Alms1m1Btlr
Name: ALMS1, centrosome and basal body associated; mutation 1, Bruce Beutler
MGI ID: MGI:5619129
Synonyms: ares
Gene: Alms1  Location: Chr6:85564513-85679735 bp, + strand  Genetic Position: Chr6, 37.48 cM
Alliance: Alms1m1Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis induced a C to T transition at base pair 85,621,275 (v38) on chromosome 6, or base pair 33,779 in the GenBank genomic region NC_000072 encoding Alms1. The mutation corresponds to residue 3,197 in the mRNA sequence NM_145223 within exon 8 of 23 total exons. The mutated nucleotide converts glutamine 1028 of the ALMS1 protein to a stop codon. (J:218964)
Inheritance:    Recessive
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Alms1 Mutation:  150 strains or lines available
References
Original:  J:218964 Chen Z, et al., Mutagenetix entry for ares. MGI Direct Data Submission. 2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory