Zfp318^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Zfp318^M1Btlr
• Name: zinc finger protein 318; mutation 1, Bruce Beutler
• MGI ID: MGI:5619130
• Synonyms: Wonton
• Gene: Zfp318 Location: Chr17:46694657-46731846 bp, + strand Genetic Position: Chr17, 22.9 cM, cytoband C
• Alliance: Zfp318^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to C transition at base pair 46,409,692 (v38) on chromosome 17, or base pair 26,191 in the GenBank genomic region NC_000083 encoding Zfp318. The mutation corresponds to residue 3,428 in the mRNA sequence NM_207671 within exon 8 of 10 total exons. The mutation results in a tyrosine (Y) to histidine (H) substitution at position 1119 (Y1119H) in the long isoform of the ZFP318 protein. (J:218965)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp318 Mutation: 82 strains or lines available

References

• Original: J:218965 Zeng M, et al., Mutagenetix entry for Wonton. MGI Direct Data Submission. 2015
• All: 1 reference(s)