Plcg2M2Btlr
Chemically induced Allele Detail
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Symbol: |
Plcg2M2Btlr |
Name: |
phospholipase C, gamma 2; mutation 2, Bruce Beutler |
MGI ID: |
MGI:5619131 |
Synonyms: |
Poseidon |
Gene: |
Plcg2 Location: Chr8:118225030-118361881 bp, + strand Genetic Position: Chr8, 64.26 cM
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Alliance: |
Plcg2M2Btlr page
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Strain of Origin: |
C57BL/6J
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Project Collection: |
Beutler Mutagenetix
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Allele Type: |
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Chemically induced (ENU) (Not Specified) |
Mutation: |
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Single point mutation
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Mutation details: ENU mutagenesis induced a T to A transversion at base pair 117,615,238 (v38) on chromosome 8, or base pair 116,948 in the GenBank genomic region NC_000074 encoding Plcg2. The mutation corresponds to residue 3,532 in the mRNA sequence NM_172285 within exon 4 of 33 total exons. The mutation results in a tryptophan (W) to arginine (R) substitution at position 1113 (W1113R) in the phospholipase C gamma 2 (PLCgamma-2) protein.
(J:218966)
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Inheritance: |
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Semidominant |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Plcg2 Mutation: |
74 strains or lines available
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Original: |
J:218966 SoRelle J, et al., Mutagenetix entry for Poseidon. MGI Direct Data Submission. 2015; |
All: |
1 reference(s) |
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